CanVIG-UK Reduced Penetrance Framework

Classification of Variants of Reduced Penetrance in High Penetrance Cancer Susceptibility Genes: Framework for Genetics Clinicians and Clinical Scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK)

The CanVIG-UK Framework for Classification of Variants of Reduced Penetrance in High Penetrance Cancer Susceptibility Genes is not yet published, however the pre-print can be accessed at the link above.

Yearly Review

Following publication of the initial guidelines, CanVIG-UK plan to review the framework on a regular (yearly) basis. This review will be documented, and any updates made as a result of yearly review will be posted on this page.