CanVIG-UK Resources
Example predictive testing template for reporting a positive CHEK2 or ATM germline pathogenic/likely pathogenic variant
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Current Version: v1.1 Jan 2024 (Updated: Minor wording change to clarify for 'Implications' and 'Result' sections)
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Previous version: v1.0 May 2022
Example predictive testing template for reporting a positive CHEK2 or ATM germline pathogenic/likely pathogenic variant
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Current Version: v1.0 May 2022
Example predictive testing template for reporting a BRCA or PALB2 germline pathogenic/likely pathogenic variant (reduced penetrance)
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Current Version: v1.1 Jan 2024 (Updated: Minor wording change to clarify for 'Implications' and 'Result' sections, added 'Reduced Penetrance' to summary box).
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Previous version: v1.0 May 2022
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Example predictive testing template for reporting a positive BRCA1 or PALB2 germline pathogenic/likely pathogenic variant
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Current Version: v1.1 May 2022
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Previous version: v1.0 June 2021
Example predictive testing template for reporting a positive BRCA2 germline pathogenic/likely pathogenic variant
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Current Version: v1.1 May 2022
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Previous version: v1.0 June 2021
Example predictive testing template for reporting a positive BRCA or PALB2 germline pathogenic/likely pathogenic variant
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Current Version: v1.2 Jan 2024 (Updated: Minor wording change to clarify 'Implications' section)
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Previous version: v1.1 May 2022; (BRCA only) v1.0 June 2021
Example predictive testing template for reporting a positive BRCA or PALB2 germline pathogenic/likely pathogenic variant (reduced penetrance)
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Current Version: v1.1 Jan 2024 (Updated: Minor wording change to clarify 'Implications' section, added 'reduced penetrance' to summary section)
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Previous version: v1.0 May 2022
Example predictive testing template for reporting a negative variant for the R208 germline panel
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Current Version: v1.1 May 2022
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Previous version: v1.0 June 2021
PREDICTIVE: Report Templates
External Resources
ACGS
The Association for Clinical Genomic Science brings together scientists working within genetics into one professional association.
JMG Paper
Cancer Variant Interpretation Group UK (CanVIG-UK): an exemplar national subspecialty multidisciplinary network.
Journal of Medical Genetics
Published: 13 March 2020.
UKCGG
The UK Cancer Genetics Group.
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A multidisciplinary organisation for UK clinicians, counsellors & scientists interested in cancer susceptibility genetics.
ACMG
The American College of Medical Genetics variant interpretation framework can be found on their website.