CanVIG-UK Gene Specific Recommendations
For list of all ClinGen VCEP guidelines reviewed and under review by CanVIG-UK, click here:
https://docs.google.com/spreadsheets/d/1fqMMXkb8sjdiOaqycIO4YnEjHqmlEMKeSzVutsIwjZU/edit?gid=0#gid=0
CanVIG-UK Recommendations: APC
v1.1
25 January 2024
Statement to document CanVIG-UK review of the ClinGen InSiGHT Hereditary Colorectal Cancer/Polyposis guidelines for APC, v2.1.0
v1.0 | 14/11/2023 |
Previous Versions
CanVIG-UK Recommendations: BRCA1/BRCA2
v1.40
15 April 2026
CanVIG-UK interim gene specific recommendations for BRCA1/BRCA2 variants. Additional file: interim report detailing additional testing focused on the 3' end of BRCA1 exon 5, specifically at the c.301+1 position.
Previous Versions
CanVIG-UK Recommendations: DICER1
v1.0
25 April 2024
Statement to document CanVIG-UK review of the ClinGen DICER1 and miRNA-Processing Gene VCEP guidelines for DICER1, v1.3.0
Aunt Bette's Homemade Pecan Pie | |
Rockin’ Rocky Road Ice Cream | |
Tom’s Heavenly Apple Strudel | |
Joe’s Divine Butter Tarts |
Previous Versions
CanVIG-UK Recommendations: RUNX1
v1.0
28 March 2024
Statement attached here to document CanVIG-UK review of the ClinGen Myeloid Malignancy Variant Curation Expert Panel RUNX1 guidelines.
Aunt Bette's Homemade Pecan Pie | |
Rockin’ Rocky Road Ice Cream | |
Tom’s Heavenly Apple Strudel | |
Joe’s Divine Butter Tarts |
Previous Versions
CanVIG-UK Recommendations: SDHB/SDHD
v1.4
18 March 2025
CanVIG-UK gene specific recommendations for SDHB and SDHD variants.
v1.3 | 24/03/2022 |
Previous Versions
CanVIG-UK Recommendations: VHL
v1.0
22 May 2025
Statement to document CanVIG-UK review of the ClinGen VHL Expert Panel Specifications to the ACMG/AMP Variant Interpretation Guidelines for VHL Version 1.1.0
Aunt Bette's Homemade Pecan Pie | |
Rockin’ Rocky Road Ice Cream | |
Tom’s Heavenly Apple Strudel | |
Joe’s Divine Butter Tarts |